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KMID : 1164220140260020337
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Journal of Korean Society for Radiotherapeutic Technology
2014 Volume.26 No. 2 p.337 ~ p.343
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Evaluation of Ovary Dose for woman of Childbearing age Woman with Breast cancer in tomotherapy
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Lee Soo-Hyeung
Park Su-Yeon
Choi Ji-Min
Park Ju-Young
Kim Jong-Suk
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Abstract
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Purpose : The aim of this study is to evaluate unwanted scattered dose to ovary by scattering and leakage generated from
treatment fields of Tomotherapy for childbearing woman with breast cancer.
Materials and Methods : The radiation treatments plans for left breast cancer were established using Tomotherapy planning system (Tomotherapy, Inc, USA). They were generated by using helical and direct Tomotherapy methods for comparison. The CT images for the planning were scanned with 2.5 mm slice thickness using anthropomorphic phantom (Alderson-Rando phantom, The Phantom Laboratory, USA). The measurement points for the ovary dose were determined at the points laterally 30 cm apart from mid-point of treatment field of the pelvis. The measurements were repeated five times and averaged using glass dosimeters (1.5 mm diameter and 12 mm of length) equipped with low-energy correction filter. The measures dose values were also converted to Organ Equivalent Dose (OED) by the linear exponential dose-response model.
Results : Scattered doses of ovary which were measured based on two methods of Tomo helical and Tomo direct showed average of 64.94 ± 0.84 mGy and 37.64 ± 1.20 mGy in left ovary part and average of 64.38 ± 1.85 mGy and 32.96 ± 1.11mGy in right ovary part. This showed when executing Tomotherapy, measured scattered dose of Tomo Helical method which has relatively greater monitor units (MUs) and longer irradiation time are approximately 1.8 times higher than Tomo direct method.
Conclusion : Scattered dose of left and right ovary of childbearing women is lower than ICRP recommended does which is not seriously worried level against the infertility and secondary cancer occurrence. However, as breast cancer occurrence ages become younger in the future and radiation therapy using high-precision image guidance equipment like Tomotherapy is developed, clinical follow-up studies about the ovary dose of childbearing women patients would be more required.
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KEYWORD
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breast cancer, Tomo Helical, Tomo Direct, scattered dose, infertility
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